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Alpha-HgH from Quality Health Blends

The Science behind Alpha-HgHTM

NOTE: The scientific basis for each of the two major components of Alpha-HgH® is extensive and rich. Many studies attest to the efficacy and safety of alpha glycerylphosphorylcholine and of homeopathic HgH. This report is but a small summary of some of the results from a sampling of the studies.

Scientific studies demonstrate the efficacy of the first component of Alpha-HgHTM Alpha-GPC

Alpha-GPC (alpha-glycerylphosphorylcholine) is a phospholipid which provides a uniquely non-electrically-charged source of choline. This lack of charge most likely accounts for its ability to pass over the blood-brain-barrier. Studies (Abbiati-1993) show that Alpha-GPC increases free plasma choline more quickly than other uncharged choline precursors.

Enzymes in the brain split a-Glycerylphosphorylcholine (Alpha-GPC) into Glycerolphosphate and Choline and easily cross the blood-brain barrier for the synthesis of phosphatidylcholine and acetylcholine, both essential for the maintenance and function of neuronal brain cells.

Another major benefit of Alpha-GPC seems to hinge on its unique molecular structure. A simple enzymatic process easily breaks Alpha-GPC into two components: Glycerolphosphate and choline. These two pieces easily pass through the blood-brain-barrier and each provides particular benefit to enhanced brain function.

The Glycerolphosphate molecule is quickly converted into phosphatidylcholine which is used to repair and replace damaged and/or aging membranes of brain cells.

Choline is used to synthesize the essential neurotransmitter, acetylcholine. Acetylcholine is the vehicle used to carry all electronic messages from the end of one nerve cell to the receptor of the next.

Through the years, many substances have been tested and drugs have been developed to enhance memory and brain function. To date, nothing seems to be as effective or have as lasting effect at Alpha-GPC.

What follows is a summary of some of the recent studies comparing Alpha-GPC with other agents.

Alpha-GPC superior to acetyl-l-carnitine in Improving Thinking and Memory

Alpha-GPC superior to acetyl-l-carnitine (ST200) in SDAT Study in improving memory and thinking skills as measured by Mini Mental State Examination (MMSE)
Results as reported by Parnetti L, et al, "Multicentre study of l-a-glyceryl- phosphorylcholine vs. ST200 among patients with probable Senile Dementia of Alzheimer's Type" Drugs & Aging, No. 3 (2), 1993.
One such multicenter study headed by Parnetti in 1993 compared Alpha-GPC to acetyl-l-carnitine (ST200) in patients with Senile Dementia of Alzheimer's Type (SDAT).

Subjects treated with Alpha-GPC obtained greater improvement of their general and cognitive conditions than those treated with ST200. In particular, Alpha-GPC treatment produced significantly better results as measured by the GGS and SCAG scales (universally-used psychometric and physiologic tests for evaluating thinking and memory ability in age-related brain dysfunction) resulting in a higher quality of life for Alpha-GPC treated individuals and their families.

Studies Show Alpha-GPC Superior to Cytidine Diphosphocholine in Improving Memory, Cognitive Skills, and Behavior Parameters

Three multicenter studies with diagnosed with Multi-Infarct Dementia, (MID), compared Alpha-GPC with cytidine diphosphocholine (CDP). The first study (Di Perri) demonstrated that Alpha-GPC was significantly superior to CDP in improving memory functions.

The second study (Frattola) showed that Alpha-GPC provides faster and more complete improvement in thinking skills, somatic functioning, memory, and word fluency.

In the third study (Muratorio) Alpha-GPC treatment significantly improved memory, cognitive skills, and behavioral parameters throughout the 3 month study. The Alpha-GPC subjects also showed very high improvement at the follow up examination 30 days beyond the cessation of treatment.
Alpha-GPC superior to Cytidine diphosphocholine (CDP) for improving memory and thinking skills in Geriatric Patients using Sandoz Clinical Assessment (SCAG) Scale

Alpha-GPC superior to Cytidine diphosphocholine (CDP) for improving memory and thinking skills in Geriatric Patients using Wechsler Memory Scale (WMS)

Alpha-GPC superior to Cytidine diphosphocholine (CDP) for improving memory and thinking skills in Geriatric Patients using Sandoz Clinical Assessment (SCAG) Scale

Alpha-GPC superior to Cytidine diphosphocholine (CDP) for improving memory and thinking skills in Geriatric Patients using Sandoz Clinical Assessment (SCAG) Scale

Clinical Trials Demonstrate Alpha-GPC Superior to Oxiracetam in Boosting Memory Ability

Two studies with a total of 90 subjects with moderately severe Age Associated Memory Impairment compared Alpha-GPC and Oxiracetam. One trial (Abbati) showed similar, positive results for both agents until the 8th post-treatment follow up week. Positive residual effects of Alpha-GPC were consistently better than Oxiracetam's results.

Alpha-GPC subjects performed much better than Oxiracetam with rating scale scores and psychometric tests in a second study (Paciaroni and Tomassini).

Animal Studies Suggest Daily Alpha-GPC Use Counters Neuron Loss and Memory Loss

Researchers (Ricci) report that daily Alpha-GPC supplementation "counteracts some anatomical changes of the rat hippocampus occurring in old age." Neurons in the hippocampus relay information to the cerebellum. There are other studies that show Alpha-GPC also helps restore acetylcholine receptor sites. The number of these important sites tends to decrease with age.

Amnesia has been directly tied to blocked or decreased levels of acetylcholine. As a result, scientists have used this phenomenon to evaluate the ability of Alpha-GPC to reverse this damage.

In a recent study (Lopez) the oral administration of Alpha-GPC reverses amnesia and partially counteracts the loss of acetylcholine in the brain induced by the drug scopolamine.

Researchers in another study (Sigala) found that oral administration of Alpha-GPC actually prevented learning impairment and was able to reverse scopolamine-induced amnesia.

Human Performance Tests Show Alpha-GPC Increases HGH, Strength and Muscle Power

Human Growth Hormone
Recent placebo-controlled tests performed by the Ohio Institute of Health and human Performance, showed Alpha-GPC doubles growth hormone response in the first 30 minutes after exercise.

Peak Force and Peak Generation
The same tests showed that subjects were able to generate approximately 14% more peak force during six sets of squats when given an oral administration of Alpha-GPC 90 minutes prior to the exercise. These subjects also produced an average of 13% more peak power during the same exercise.

Based on the researchers' discovery of a lower Respiratory Exchange Rate (RER) levels in the same subjects, they suggest that Alpha-GPC may also increase fat metabolism during the post-exercise period.
Alpha-GPC Doubles Post-Exercise Human Growth Hormone Output

Alpha-GPC Produces Substantial Increase in Peak Bench Press Force

Alpha-GPC Produces Substantial Increase in Peak Power

Alpha-GPC Produces Substantial Increase in Peak Bench Press Force

Scientific studies demonstrate efficacy of the second Alpha-HgHTM component — Homeopathic HgH

Several studies have confirmed and reconfirmed that injectable HGH provides many age-reversing benefits. The question remains, can a homeopathic form of HGH produce the same effects? This is an important question because the cost of injectable HGH therapy puts it out of reach of most — without even considering the fact that many are adverse to injections in the first place.

A few researchers have attempted to answer this question. One such study (Brewitt) was lead by a former researcher at the National Institutes of Health. The study included a set of three double-blind, placebo-controlled trials. These researchers found that homeopathic HGH significantly increased body mass and simultaneously decreased overall body weight, body fat, increased mental clarity, increased libido, improved breathing, improved skin softness, and improved sleep quality over those in the placebo group.

One of these trials, a 21-day double-blind, cross-over study, concluded that homeopathic HGH significantly increased lean body mass and simultaneously decreased overall body weight, body fat, and blood pressure.

Another study (Culik) measured the change in serum IGF-1 levels in a 30-day double blind study with homeopathic HGH. Insulin-like Growth Factor 1 (IGF-1) is a polypeptide protein hormone produced in the liver, usually in response to the presence of HGH. Because HGH only remains in the blood for about 20 minutes, researchers most often monitor IGF-1 to determine the amount of HGH that is produced over time.

The Culik study measured an increase in IGF-1 that was nearly 2.5 times that of the placebo controls. In addition, subjects rated changes in a group of 10 clinical areas tied to increase of serum HGH. Subjects receiving homeopathic HGH reported significant improvement in 7 of the 10 areas. The researchers concluded that oral administration homeopathic HGH did indeed contribute to beneficial increases in HGH levels.

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Abbati C. et al, “Neurotropic therapy of cerebral aging,” Advances in Therapy, Vol. 8, No. 6, Nov-Dec 1991.RETURN

Abbati C. et al, “Neurotropic therapy of cerebral aging,” Advances in Therapy, Vol. 8, No. 6, Nov-Dec 1991.RETURN

Anekonda TS, “Resveratrol—a boon for treating Alzheimer’s disease?” Brain Res Rev (2006) Sept; 52 (2): 316–26.RETURN

Afaq F, Mukhtar H, “Botanical antioxidants in the prevention of photocarcinogenesis and photoaging,” Experimental Dermatology (2006) 15 (9): 678–84..RETURN

Baliga MS, Katiyar SK, "Chemoprevention of photocarcinogenesis by selected dietary botanicals," Photochemical & Photobiological Sciences (2006) 5 (2): 243–53.RETURN

Baur JA, et al, “Resveratrol improves health and survival of mice on a high-calorie diet,” Nature (2006) Nov; 444 (7117): 337–42. RETURN

Brewitt, et al, “Three Double-Blind Placebo-Controlled Studies,” Alternative and Complementary Therapies, Vol. 5, No. 6, December 1999.RETURN

Di Perri R., et al, “A multicentre trial to evaluate the efficacy and tolerability of a-glyceryl-phosphorylcholine vs Cytidine diphosphocholine in patients with vascular dementia” The Journal of International Medical Research, 1991, 19.RETURN

Frattola L. et al, “Multicenter clinical comparison of the effects of choline alfoscerate and cytidine diphosphocholine in the treatment of multi-infarct dementia,” Current Therapeutic Research, Vol. 49, No. 4, April 1991.RETURN

Karuppagounder SS, et al, “Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer’s disease,” Neurochem Int (2009) Feb;54(2):111-8.RETURN

Kumar P, Padi SS, Naidu PS, Kumar A, “Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms,” Behav Pharmacol (2006) Sep;17(5-6):485-92.RETURN

Lagouge M, et al, “Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha,” Cell (2006) Dec;127 (6): 1109–22.RETURN

Lopez CM, et al, “Effect of a new cognition enhancer, alpha-glycerylphosphorylcholine on scopolamine-induced amnesia and brain acetylcholine,” Pharmacol Biochem Behav, Vol. 39, No. 4, pp 835-40, Aug 1991.RETURN

Muratorio A. et al, “A neurotropic approach to the treatment of multi-infarct dementia using a-glyceryl-phosphorylcholine,” Current Therapeutic Research, Vol. 52, No. 5, Nov. 1992.RETURN

Paciaroni E., Tomassini P.F. “Clinical trial on efficacy and tolerability of a-GPC (choline alfoscerate) controlled versus oxiracetam in patients with mild to moderate mental decay of vascular origin,” Giornale Italiano di Ricerche Cliniche e Terapeutiche, Vol. 14, No. 29, 1993.RETURN

Parnetti L, et al, “Multicentre study of l-a-glyceryl-phosphorylcholine vs. ST200 among patients with probable Senile Dementia of Alzheimer’s Type” Drugs & Aging, Vol. 2, No. 3, 1993.RETURN

Ricci A et al, “Oral choline alfoscerate counteracts age-dependent loss of mossy fibres in the rat hippocampus,” Mechanics of Ageing Development, Vol. 66, No. 1, pp 81-91, 1992.RETURN

Sharma M, Gupta YK, “Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats,” Life Sci (2002) Oct 11;71(21):2489-98.RETURN

Sigala S, et al, “L-alpha-glycerylphosphorylcholine antagonizes scopolamine-induced amnesia and enhances hippocampal cholinergic transmission in the rat,” European Journal of Pharmacology, Vol. 211, No. 3, pp 351-358, Feb. 1992.RETURN

Sinha K, Chaudhary G, Gupta YK, “Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats,” Life Sci (2002) Jun 28;71(6):655-65.RETURN

Tomé-Carneiro J, et al, “Grape Resveratrol Increases Serum Adiponectin and Downregulates Inflammatory Genes in Peripheral Blood Mononuclear Cells: A Triple-Blind, Placebo- Controlled, One-Year Clinical Trial in Patients with Stable Coronary Artery Disease,” Espín Cardiovasc Drugs Ther. (2013) February; 27(1): 37–48. RETURN